Tylosin
- CAS NO. : 1401-69-0
- CAT NO. : PH-API-1690
Melting point: 135–137 °C
Optical rotation: [α]ᴅ²⁵ –46° (c = 2, methanol)
Boiling point: ~796.05 °C (rough estimate)
Density: ~1.1424 g/cm³ (rough estimate)
Refractive index: ~1.5280 (estimate)
Storage conditions: Sealed in dry, 2–8 °C
Solubility:
DMF: 30 mg/mL
DMSO: 25 mg/mL
Ethanol: 30 mg/mL
Water: soluble, ~50 mg/mL
Form: Crystalline solid
pKa: 7.73 (H₂O, t = 25 °C, I = 0.167, uncertain)
Color: White to light yellow
Stability:
Solutions stable at pH 4–9 (most stable at pH ~7)
Below pH 4 → Tylosin B (desmycosin) forms (acid hydrolysis)
Neutral/alkaline pH → Tylosin aldol (TAD) + other polar degradation products
Exposure to daylight → photodegradation to isotylosin A (isoTA)
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